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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d05b32ae8033c99658174d3a1d98bcef0179bdd34ee1faac651615d354bbd4' 
  AND token = 's41VjsCX6sWCiqGMyumQ0uInLUbdqrngJhSb5GFAQn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}