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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a750bb0827fc7046e3158bf80d5a25787b37fac0baef256fa5181a41f3295708' 
  AND token = 'GOXEuHiqsTHE9/g0asLgYj8zVGXU1IDa5WIOiT7xDkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}