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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0451e19eef45d32bc7a17bf51360d2e207d9353aac8679c894d4548e39bed42' 
  AND token = 'V8sCUSoVabK7pZDaosS+IoywWhZDi8uSvdobbbJuXo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}