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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8682a2bffb5947e1e011f699d4a52146f5f7d041f0da6f80d9d6482a5c6196c7' 
  AND token = 'Xer+ZQDf32wNALD7HCeywI1z86EKWgPvzeu9v+OZYkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}