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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acee1f5b1185c2b981d8240a63c40ab557a26708a3762f8540780c1eb9509382' 
  AND token = '0BjeBisUsnh2cMX+NaptVayRazpThdOsl2mRGqrWkMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}