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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d6ab051e0a011722a7cf03d02bca25907941174aac6553d1ddd1a8b16ab001' 
  AND token = 'fHmtK1x5qAtMf8lPGqSYQfg2kraW4fJTMQRvjY3+kvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}