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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5ee0a1cb504ef56eb11f63390453db3f7537204d2b2af57aa6fc9a3c8caf6b' 
  AND token = 'ZOvkKpd0F8w5RUqF012hhmOluLjERV0tgbDbig27uRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}