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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e4841e7ac0a62fcb16dbf2ce8c2667f06e6465abe42af1900cb095dd88c2ed' 
  AND token = 'Cskr4rWbAfbfIWPybkLp9lG4QBMUwDjD+qBlx1FCKcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}