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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451b258b39f8b1f5694da7dbafa1bd6767892d8653f3a367ed7227a20c23b9e5' 
  AND token = 'RtQpfIyWf1q6Xv3Mg6WwNGwVWQ6lb18FeRkYGeL8NyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}