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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e28d053c4a4881d3cbcc626d2e252549db6b8cd82e03acf6d40b56aca7b9dd9' 
  AND token = 'OY4rB8/x01/Ahc3CIuxxeAAVO33uePUv+v2N8ZzTQBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}