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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3373b28a98312343a6b7f03609bd1a099cc08a213faeaffb53450f97e6209db1' 
  AND token = 'DSPQmYm1ZE7ie3hPuAcajJU3iLOqxubNDQ1vsEpPLjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}