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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7c0b51cba6bc6738f69d11e407d56a46c194c1deb19347f3579cfa41ec7d78' 
  AND token = 'vLMiNVWco22dkzut3yE1F9sNS6NFGIEh77xwBCmYm+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}