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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f1a905f69f8635dbec3bbce7a54e649ad46afe8870f7b55ed152619d9030e6' 
  AND token = '+CHx9Pum02F7YeLInMp5TPB3QN5AO9BYF2YLOqcpyVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}