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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa44239d5e72c936aac3cd91d6d168136166a26785b242c4cd13d6254d4daa9b' 
  AND token = 'vpO4WC9YC2uRQwXtdgh+XgB2dL3Eol41ZaC1BzgFPNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}