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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25c1b0c54e38efddb25fc8417f4afc998b2d02ebfd191b224b64697d1116b97' 
  AND token = 'gaNr4T9xrin1sDrcnQI+HzKXd+HqiqyZUl1G1v2ybdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}