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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a15d2c3a18c79d59e43c6deb5f0ea2a024bd864f6865ed6f790f53657ff3a82' 
  AND token = 'D9FWvVG5h47HSGaiiSHwWORvRA7g5mWDDAHlgUbCZHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}