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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e55ecd85d91107b042799e0f18d533a35a6191fc2f380e8f1f549f4b88640e' 
  AND token = 'xsJ+b9ZILhvQfvcW0QzbtG8m8B5Vcl0v2ufUS+1UyZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}