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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e045981488a804e8cf3efc44e33e8b51bd175213a578be3e5493b5f884fc22ed' 
  AND token = 'Ny+Ye4Ky+awXBNDsZb/fWupnK8zf6TEN+W6LbqSTuY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}