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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33282a2e8af63a24a7907edf0244c5d1bcbef7df46afc06844818cef46a165cf' 
  AND token = 'c+tx84IHFYz7dXy5vApWiThLenHKo8p5/i2ziNSwMTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}