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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2721ab98ec9828aff446f44594c2900f41a3108cc786b61d2bc3db087b64c79' 
  AND token = 'jvgHhMa4bjRyZ6dLcq1OuPcNM46MWbidCezWCeP8q+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}