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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ddf44200f8d2282f7b8efd0d6ff8d689788687d13dde8b17566e277f5f4fae' 
  AND token = 'RFqo//8cRmmxScmM5VfgAu8miTzoTJ/46LoaMRLXLyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}