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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681ae5103bfd8456f2f1b277aad6fcef5f1e6a31ecf1f13b46db26ea7bba3c13' 
  AND token = 'Ewt1q7q+asM5uFilYfGMw9jjIBKmxe56q7kq4uHiWW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}