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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d523399fe12810e5c4447a6f73c786a0585689ed974f47088efaeb5d226a2f' 
  AND token = 'o7XKc/VWzrlKAzWJyW4vwQr25BbR4/olrEUKeAWMDzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}