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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c5c43c1c6ae05714cd1aee60a38ede5d5fb265b95bf9be0c6e51f3f5ff9afb' 
  AND token = 'ZwNuLBRS8KHHZp7uhSVhGs+Zv0MeFcroruDuk5dV9q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}