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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bf152026c9676b8fcc1e628a79038008b31bde40e4d3b90838749528334f6a6' 
  AND token = 'IMAnIKnXPdpJXadbDgFc3q+KGwscz7sZntZODGbWZ+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}