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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7512ba129019a0cde94909d36d3d7b276ddf6617e8cfb1b933bf0be3cf23e5f' 
  AND token = 'F6Nh0pRV3lo/P8EP4a9rfVmGeQQrrmHOSKMISw6kJC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}