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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ed723c28fdf01e8ed8372cc8de2011143db0f51814905fb728be66f8dff579' 
  AND token = 'U8L0zfUK/bmfFKN2iqU6MqlpEJHrLOT7fgLiMnSLr/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}