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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a99d4c381409d46458533f34a6ed001365fba428885b89abce1887066540c5' 
  AND token = 'cusS8yAU298o/hiC/o/e1ovcFvCyGh3flMyMr6/06Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}