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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43de44ac2a01c08ff10bc5b80cda4ff6b26cd4204091f378dfbc11ef1ecdd76b' 
  AND token = 'cMIuIvrq4tUVEbkYqjlhNGttoFqhc7pooL93wMDuLWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}