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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66e6ea3390238bc683f16bef1247cf360d3f329e87c4ef0225244467a95c8d5' 
  AND token = 'jYxt6kEPBTUy6d1LTA/bbuzzAyPJpC4PjURg9IeAyBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}