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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80ead717d582d95d4bb9868455f1493f3060db5f3308e1e3637187bd785a7b6' 
  AND token = '1zrrC2HUfKf+6sCjvdrbuTB3IZTdB1/WDe3uCNzVbPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}