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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605ad79d2c77db1f2a13ab0a23e36daedbdb3f4ec09f0a763fb7e8400c89e488' 
  AND token = 'r08o8OEX00zINyxcUWgfVEwtQuqjeYCFFqcVqMb0FTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}