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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de5e3754b52be1cd632674068881d1e68c19e0edf2d3c1b12405d8eeda086c1' 
  AND token = 'XUcr9jJDIPO2DY4MkckpMNg29JDoskQjfpLmUKE11Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}