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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3d3a5eec17238d3869f4e06145ce2f8b712b099ab692fac2aae83d1b842e94' 
  AND token = 'AoW66b2/0AzKAuw1bTjFR8z+VKGc9bv0ufZnaasFCzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}