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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4cf483119c142274f93fd7e4f1d2e743edf192b80c6a0cd1cf275b632bd8e21' 
  AND token = 'UvpqNow0UcAlouFGuLJNylikepDrx5BQ/tgoz3tgHpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}