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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101aef6c7733247055469f14dbeb42137c6ccfc2eab4738b6dd18d3812cf42a7' 
  AND token = 'db9dnxlsJDzSVl3lF2Q7OWxdvIH/JSiGjLG4moGsuT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}