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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81b3b004662fefc3d3e18677a5126913646a45bda571097cfc24cadf9bbd494' 
  AND token = 'D1En++0G7Gc5HIDzWx9By6bViK+sUma8MZmYA64uKSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}