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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4d7204c48c29b628d8034eb9d2697dbff997df7383c7accd228b441bed5340' 
  AND token = '0M/a6p890ZirFPpkD+ZCweQq4uAlsIwZPw9nEz9snx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}