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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f60b7ec4ee37b57252258d1b179ff7fb5987c99f19f85e6603e229558f9e4508' 
  AND token = 'r3bj7LRLgtJiMlHWGwluEC25TkaQfISBtg2rz258bi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}