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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b07106f39f8f9ce50156fbe2597281debffb3f17c32129a726a43b2e08d13b6f' 
  AND token = 'ZSz+wpPoHBzeru8eJMXsZ0oYl4g8uN1GeFElBxwg51w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}