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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '675a4767848e2416e71c63f88ac84c00da37b46e82d508cc08dcbdf42f201ec1' 
  AND token = 'nKnRB87Q+kGUZxkk1nNmHarstFJCxxFh7BBouJJ+ABI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}