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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851435ef0f17249fee9dc3372ed7de52d921dcec1432437aad5af848cb8595ae' 
  AND token = 'MkSt4cUlBsT43D4N1qsc4y/hmL9b+PO/0NY71tcRw8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}