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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c37b7533ec317a79fd2ebcbb04c826cb20875509a8c177dfcc1548c6b02e609' 
  AND token = '+38+809k3BIgsZIvYqdvYmeYfum+Gdw15/EEs1tcnw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}