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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ffdc73d793c6613cbc0f654445a3b38abbb2a9c830ce430a6b78d15ea6b21de' 
  AND token = 'ptCItjh5zNxR1ZqEuY5ig01zoWNw+LcGlj6yxa7hbMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}