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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3ec836049f32ceabf663e6f86a393dc00597e66d730cfab995ab504f0b6f7c1' 
  AND token = 'iPrQaRH2t5mNkEOcPRRXunh6UylYu09WF8Gv87k2dcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}