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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b66f6322ecdc28e9e45be2c84fb5aa18ea59cc43eeb4e4e40979935d80c1325' 
  AND token = 'tutyjDkpfwQdiof+jbK0p0HID89UL6d6V+g17uM7B6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}