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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f778205cab5340af4f073bb49be81580100aa9a8f2b5c96592e4e3d153afcb3' 
  AND token = 'K45kHE4WX356mPJRQOguLH0hvF5Fbg3zxkfJ6MAdxEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}