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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f620537440ee1b2505a382802d32df26b38f113329d5c039e1714dbacbdea82b' 
  AND token = 'UPpGCqkcMP+i7J7qyXwYRRrrN6o0ZVNkBufCVM7PVGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}