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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817df8c2e1c4ec4b3bc80a86817b9173a485974b6e9c9a8e456f10a9905d5f5b' 
  AND token = 'HEpRt/kBBsfrMCdqaSI4TaR9ExtsAAMKZghlaHk6IR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}