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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd345bfbc5985a67970a637055a3fde8e49d56751b03a4cf7dbe2fd858914ba53' 
  AND token = 'IMdvvFovDKA5WEwn2WEZ+2f/BPX13ZQX3emqUWr+Dls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}